Our mission is to extend the healthspan of the next generation

Today, over 100 million Americans suffer from at least one chronic disease. With no cure, our friends and families are leashed to treatments that address symptoms rather than root causes. 

Our aim is to slash incidence rates of disease in the next generation. We detect risk at the earliest stages, and give couples the ability to tilt the odds toward extending their children's healthspan - the number of years of life uninterrupted by disease.

What we do

Working to give everyone the ability to have a healthy child

Orchid is a reproductive technology company working to give everyone the ability to have a healthy child. We are doing the difficult work of measuring and mitigating genetic risk—so the next generation can concentrate on life, not managing a disease.

Building ultra-high resolution genetic reports

We're building ultra high resolution genetic reports so that, for the first time in human history, prospective parents can protect their future children from inheriting a predisposition to the most common diseases -- not just rare ones. 

Life is short, do work that matters.

All roles are remote-friendly. We are based in San Francisco.

What we offer

  • The opportunity to have a trajectory-altering impact on humanity

  • The opportunity to grow rapidly and influence engineering, product, and the strategic direction of the company.

  • Competitive compensation (base, equity, generous benefits)

Expand the accordion
Senior Statistical Geneticist

Remote

We are looking for a remarkable statistical geneticist that enjoys being self-directed and identifying the most important problems to solve.

You will:

  • Lead the development, validation, and translation efforts to deploy polygenic risk scores into clinical reports. 

  • Use cutting edge statistical approaches, large datasets (public and privately obtained through collaborations) to build workflows and processes that ensure high quality results are returned consistently.  

  • Be the primary contributor for scientific collaborations with academic, nonprofit, and industry partners, and lead a multidisciplinary team focused on achieving these aims.

You have:

  • A PhD in a quantitative or computational field (statistics, genetics, computational biology, or similar)

  • A demonstrated ability to use and develop cutting edge methods for analyzing human genetic data

  • Planned and executed rigorous statistical analysis on large scale genetic data sets (e.g. ExAC/gnomAD, UK Biobank, UK10K, EBI GWAS Catalog, 1KG, etc.)
  • Experience with genetic association testing (GWAS) or post-association analysis using summary statistics (fine mapping, colocalization, LD score regression, meta-analysis, etc.)
  • Fluency with the tools of the modern computational biology, including coding in Python, R, or C/C++ and the statistical models used to develop new insights or predictions.
  • A strong track record of producing high quality research.
  • Confidence presenting your work to technical and non-technical audiences.

You are:

  • A builder. You can start from a blank screen, define the right questions, and deliver solutions. 
  • Ambitious. You want to be given enormous responsibilities and the opportunity to do the best work of your career. 
  • Optimistic. You can envision how deliberate effort, consistently applied, can yield a remarkable outcome. 

You (may) have:

  • A track record of translating scientific results into new products

  • Successfully recruited and built great teams


To apply, send an email to Noor at noor@orchidhealth.com with the subject line "Senior Statistical Geneticist". Please include 2-3 bullet points on your most significant technical contributions to a recent publication, and links to help us learn more about yo (Google Scholar, GitHub, personal website).

Expand the accordion
Bioinformatics Engineer

Remote

We are looking for an engineer who loves building complex systems. We value people who can quickly obtain a deep technical understanding of new domains, and enjoy being self-directed and identifying the most important problems to solve.

You will:

  • Work collaboratively with our lab leadership to provide timely bioinformatics support with attention to detail and clear communication; build repeatable and automated processes when possible

  • Define a system to organize our validation samples and how they should be used as our company scales (wet lab protocol adjustments; higher case volume, etc)

  • Help execute on critical bioinformatics roadmaps, including hard-to-dos like SMA, FragileX, and exon deletion
  • Support the execution of NGS studies for internally- and externally facing projects to advance academic collaborations
  • Configure and use modern bioinformatics tools (GATK, Sentieon, etc) to analyze and interpret large NGS datasets
  • Collaborate in an interdisciplinary fashion across R&D, engaging in the process of experimental design considering both computational and molecular sides of a project
  • Effectively communicate computational topics and project outcomes both internally and externally

You have:

  • Masters degree or equivalent industry experience in Bioinformatics, Computer Science or a related field, additional industry experience preferred

  • Expert status in whole genome sequencing analysis

  • Expert status in the development and application of bioinformatics algorithms, tools, and pipelines for DNA analyses (e.g. SNVs, INDELs, and CNVs)
  • Expert working knowledge of Python and familiarity with R, comfortable working in large, structured, production-grade codebases with multiple contributorsExperience with one or more bioinformatics workflow orchestration solutions (e.g. Nextflow, snakemake, or CDL
  • Working knowledge of commercial and publicly available biological databases including NCBI, Ensembl, ArrayExpress/GEO, GTEx, gnomAD, TCGA, and/or SRA
  • Experience with data science APIs, tools, and frameworks such as Keras, scikit-learn, NumPy, SciPy, containerization, version control, and MLOps
  • Demonstrated ability and enthusiasm for working in a multi-disciplinary team setting

You (may) have:

  • Strong track record of independence, innovation, and productivity demonstrated through multiple peer-reviewed publications, grants, or patents


To apply, send an email to Carly at carly@orchidhealth.com with the subject line "Bioinformatics Engineer". Please include links to help us learn more about things you've built (GitHub, GoogleScholar, personal website, LinkedIn).

Software Engineer - Generalist
Expand the accordion

Remote

We are looking for a strong generalist that is interested in exploring technical problems in a variety of domains, such as front-end, backend, machine learning, performance, infrastructure, or web technologies in general. We want this person to be radically ambitious and eager to make an impact. If you are enthusiastic about any of the following — the company, biotech, genetics, health, startups, or becoming the best version of yourself — this is the place for you.

You will:

  • Work in cross-functional teams to architect and build features that will create the most value for users

  • Architect and ship completely new products, like genetic testing for embryos
  • Engage in user feedback debriefs with our CEO
  • Build features across the stack -- front-end and backend
  • Integrate with and build machine learning systems and workflows
  • Create solutions in at least one of the following areas: bioinformatics pipelines, logistics & order fulfillment, patient portal & onboarding, or scaling web services
  • Integrate with external software partners and APIs for DNA sequencing, logistics, scheduling, payments, and more

You have:

  • Experience building software products that impact users

  • Willingness to debug problems across the stack, scuh as performance problems and deployment issues

  • Experience as an early-stage engineer or founder, or enjoy fast-paced work environments with tight feedback loops

You (may) have:

  • 2+ years of experience with UX development or web services and application development

  • 2+ years of experience in web development (frontend or backend), machine learning, or infrastructure engineering

  • Proficiency in Python
  • Proficiency in Javascript and web frameworks
  • An interest or willingness to explore machine learning problems at scale
  • Experience with large-scale production or research workflows
  • Proficiency in engineering across the stack, possibly including: Javascript, web frameworks, dev ops, performance engineering, high performance computing, cloud technologies, QA / test engineering


To apply, send an email to Noor at noor@orchidhealth.com with the subject line "Software Engineer - Generalist". Please include links to help us learn more about things you've built (LinkedIn, GitHub, personal website).

Expand the accordion
Senior Data Scientist

Remote

We are looking for an engineer who loves building complex systems. We value people who can quickly obtain a deep technical understanding of new domains, and enjoy being self-directed and identifying the most important problems to solve.

You will:

  • Work with our statistical geneticist to select and validate genetic risk scores

  • Conduct analyses of large-scale genetic data to understand patterns of disease risk in large populations

  • Evaluate and improve risk scores via pruning
  • Work with research engineers to scale genetic data processing

You have:

  • Experience working with or developing complex production systems that involve large volumes of data

  • A willingness to dive deep into data to understand patterns and anomalies in genetic data

  • 4+ years of experience in data science, backend, machine learning, or infrastructure engineering
  • Proficiency in Python

You (may) have:

  • Experience analyzing "big data" or scientific data

  • A solid understanding of good experimentation practices for solving applied research problems

  • Experience implementing or productionizing research code
  • Proficiency in engineering across the stack, possibly including: Javascript, web frameworks, dev ops, performance engineering, high performance computing, cloud technologies, QA / test engineering


To apply, send an email to Noor at noor@orchidhealth.com with the subject line "Senior Research Engineer - ML". Please include links to help us learn more about things you've built (LinkedIn, GitHub, personal website).

Product Designer
Expand the accordion

Remote

You can transform raw ideas into product designs. You care deeply about user experience and have excellent visual design skills. You are a self-starter, self-motivated, and able to execute even when sometimes given very broadly defined, loose projects ideas.

You have:

  • Expertise in either UI, UX, or visual design, and skilled in more disciplines across product design

  • Enjoy striking a balance between functional and aesthetic design

  • Enjoy prototyping across the design stack

You (may) have:
- Experience as an early-stage founder, or enjoy fast-paced work environments with tight feedback loops

To apply, send an email to Noor (CEO)  at noor@orchidhealth.com with the subject line "Working at Orchid: Designer". Please include links to help us learn more about things you've designed (Dribbble, personal website/portfolio).

Head of Growth
Expand the accordion

Remote

Lead growth and digital marketing for a company changing how we conceive. Orchid allows couples to change the trajectory of their future child's health with the highest resolution genetic reports + embryo prioritization.

You will be charged with:
(1) growing our customer base / sales
(2) managing all paid channels
(3) optimizing retention activity
(4) managing / leading all agency, in-house, and contracting resources.

This role will require you to design, measure, and test  the impact of all potential channels for acquiring users. You'll flex your creative side as well as your analytical and metrics-driven nature. Furthermore, outside of digital marketing you will shape Orchid's product, brand image, PR, partnerships, and more.

You are:
- Creative, quantitative, scrappy, diligent, and ruthless.

You have:

  • A track record of leading major, measurable wins.

  • 3+ years in Growth/Performance Marketing at growth-stage or early-stage tech companies

You (may) have:
- Experience as an early-stage engineer or founder, or enjoy fast-paced work environments with tight feedback loops

To apply, send an email to Noor (CEO)  at noor@orchidhealth.com with the subject line "Working at Orchid: Head of Growth". Please include 2-3 bullet points quantitatively describing your wins in a prior role.

Director of Communications
Expand the accordion

Remote

You can author, promote, and distribute content that engages and educates customers. You are analytical and process-oriented in measuring growth and conversion. You are a self-starter, self-motivated, and have enough experience to tell us what we need to do to be successful. 

You have:

  • Experience managing social media and content strategy AND execution 

  • Experience using metrics to test and refine content strategy, discover new channels, and allocate where marketing resources will yield highest return

  • A proclivity to thrive in face-paced work environments with tight feedback loops


To apply, send an email to Noor (CEO)  at noor@orchidhealth.com with the subject line "Working at Orchid: Director of Communications". Please include links to help us learn more about you (writing portfolio, LinkedIn, personal website).

Director of Special Forces
Expand the accordion

Remote

We are looking for a ludicrously effective person to join our team as a cross-functional player putting out fires as they crop up. The ideal candidate is strategic, a systems thinker, and thrill seeker excited to be exposed to all aspects of the business, and unphased by taking on daunting new projects each day.

You can:

  • Deliver results consistently under a tight timeline. Given an ambiguous, exploratory task, you can quickly come up with a strategy and process around getting answers back to the team. You are an unrivaled individual contributor, but you can also sense when it makes more sense to hire out a piece of a project. You can draft a brief, source applicants, interview, hire, and manage a project from vague inception to decisive completion.

  • Become an expert on a new topic quickly. You know how to acquire knowledge in a new domain - what to read, where to look, who to talk to.

  • Write and speak persuasively and confidently. You're versatile - you can speak to an audience of experts and to the general public, you can negotiate and craft partnerships with our allies and enemies.

You (ideally) have:
- A technical degree (engineering, sciences) 
- Experience as an early-stage engineer or founder
- High grit and low ego

To apply, send an email to Noor (CEO) at noor@orchidhealth.com with the subject line "Role at Orchid: Director of Special Forces". Please include 2-3 bullet points describing something you pulled off faster and/or with a lower budget than anyone thought imaginable. Also include links to help us learn more about you (writing portfolio, LinkedIn, personal website).

Life at Orchid

We're a low-ego team of optimistic builders who care deeply about helping every couple have a healthy baby, and we’re looking for exceptional individuals to join the team.

Add to humanity's capabilities

At Orchid, we're working on bringing a new capability for humanity online - the ability to measure and mitigate genetic risk for the diseases that matter most. Instead of health being a genetic lottery at birth, we want every prospective parent to have the information and choice to protect their child from inheriting health risks.

Do the most significant work of your career

Having a child is a big step in life. Your work directly contributes to a life altering moment for prospective parents and has the potential to bend the trajectory of a child's life toward a healthier future.

Why Now?

Genomic datasets are exploding in size

In 1990, we started without the ability to even read the 3.2 billion letters in the human genome. We spent 13 years and $3 billion dollars assembling the very first sequence. Since then, the cost of sequencing has plummeted, enabling millions of human genomes to be assembled, often paired with physician-verified diagnoses. The goal of genomic medicine is on the cusp of realization - we have a newfound ability to measure genetic susceptibility for the most common diseases.

Define a new category

Historically, we haven't been able to move beyond rolling the dice to determine health outcomes in the next generation. Be a part of defining a fundamentally new category of precision medicine. Today, we have the opportunity to give parents high resolution data to stack the odds in their child's favor - against diseases that have burdened families for generations. 

The Team

Orchid is led by world-class experts in statistical genetics, computational biology, and fertility committed to helping families understand and mitigate their reproductive risks.

ORCHID SCIENTIFIC ADVISORS
Developed by world-class experts
The technology behind Orchid has been developed by experts in medical genetics, embryology, and assisted reproductive technology.
Jacques
Jacques Cohen, PhD
Pioneering Embryologist and foundational figure in IVF and ART innovation
jan
Roohi Jeelani, MD
Double board certified Reproductive Endocrinologist and Infertility Specialist (REI)
jan
Lusine Aghajanova, MD, PhD
Clinical Assistant Professor at the Stanford Medical Center
Barry
Barry Behr, PhD
Professor of Obstetrics and Gynecology Emeritus at the Stanford Medical Center
jan
Jonathan Kort, MD
Double board certified Reproductive Endocrinologist and Infertility Specialist (REI)
Jarry
Jerry Lanchbury, PhD
Expert in immunogenetics, 100+ peer reviewed publications
jan
Jan Liphardt, PhD
Professor of Bioengineering at Stanford University
jan
Nathan Slotnick, MD, PhD
Perinatologist and Medical Geneticist

Investors

George Church
Professor of Genetics at Harvard Medical School and MIT
Elad Gil
Entrepreneur and Investor, Co-Founder of Color Genomics
Vitalik Buterin
Co-Founder of Ethereum
Anne Wojcicki
Co-Founder & CEO, 23andMe
Carlos Bustamante
MacArthur Award Winning Geneticist
Brian Armstrong
CEO of Coinbase, Co-Founder of NewLimit

Orchid is backed by the top founders in technology and health - including the founders of Coinbase, Counsyl, 23andMe, Flatiron, Eventbrite, Oscar, and Clover - as well as Refactor Capital, Day One Ventures, and Village Global.