Expert guides on all things genetics & fertility

Whitepapers · 6 min read

Whitepaper: Validating Orchid’s Psoriasis Genetic Risk Score

Orchid's reports include a genetic risk score (GRS) for psoriasis, validated on UK Biobank data. We share our methods and findings, including how the score stra…

Whitepapers · 6 min read

Whitepaper: Validating Orchid’s Rheumatoid Arthritis Genetic Risk Score

Orchid's reports include a genetic risk score (GRS) for rheumatoid arthritis, validated on UK Biobank data. We share our methods and findings, including how the…

Quick Guides · 5 min read

Risk of Birth Defects with Age: What Prospective IVF Parents Should Know

Medical research has established a clear link between advancing parental age – especially maternal age – and increased chances of certain birth defects. Older e…

Whitepapers · 6 min read

Whitepaper: Validating Orchid’s Schizophrenia Genetic Risk Score

Orchid's reports include a genetic risk score (GRS) for schizophrenia, validated on UK Biobank data. We share our methods and findings, including how the score …

Whitepapers · 6 min read

Whitepaper: Validating Orchid’s Class III Obesity Genetic Risk Score

Orchid's reports include a genetic risk score (GRS) for class III obesity, validated on UK Biobank data. We share our methods and findings, including how the sc…

Quick Guides · 2 min read

The Most Common Neurodevelopmental Disorders

For prospective parents considering IVF, it’s natural to worry about neurodevelopmental disorders and how they might affect your future child. The good news is …

Whitepapers · 7 min read

Whitepaper: Validating Orchid’s Type 1 Diabetes Genetic Risk Score

Orchid's reports include a genetic risk score (GRS) for type 1 diabetes, validated on UK Biobank data. We share our methods and findings, including how the scor…

Whitepapers · 7 min read

Whitepaper: Validating Orchid’s Type 2 Diabetes Genetic Risk Score

Orchid's reports include a genetic risk score (GRS) for type 2 diabetes, validated on UK Biobank data. We share our methods and findings, including how the scor…

Quick Guides · 3 min read

What Causes Neurodevelopmental disorders?

Causes for neurodevelopmental disorders can be grouped into genetic influences, environmental exposures, and other risk factors. Understanding these can help fa…

Quick Guides · 3 min read

What Causes Pediatric Cancer?

Pediatric cancer refers to cancers occurring in children and adolescents (typically under age 19). It is relatively rare, affecting about 400,000 children globa…

Quick Guides · 3 min read

What Having a Sibling with Autism Means for Your Future Children

Autism Spectrum Disorder (ASD) does have a genetic component, and family history can play a role. This post breaks down what science says about family autism ri…

Quick Guides · 4 min read

What is Neurodevelopmental Delay?

This article provides a clear definition of neurodevelopmental delay, outlines common symptoms and causes, and discusses potential long-term impacts for affecte…

Quick Guides · 3 min read

What Is the Most Common Pediatric Cancer?

Each year, only a few thousand children in the United States are diagnosed with leukemia, making it the leading childhood cancer by incidence but still relative…

Whitepapers · 15 min read

The Impact of Family History on the Lifetime Prevalence of Disease

A family history of a disease often increases the odds that a child develops the same disease. We explore how family history impacts disease risk and how embryo…

Whitepapers · 16 min read

Improved Polygenic Prediction with Multi-Ancestry and Multi-Trait GWAS Data

We describe a method to improve the performance of genetic risk scores (GRS) across multiple ancestries – including European, East Asian, South Asian, and Afric…

Fertility & Pregnancy · 7 min read

How Age Affects Fertility

This guide explains how both maternal and paternal age can play a role in reproductive risks and how Orchid is uniquely placed to help prospective parents scree…

Genetics · 6 min read

Can Autism be Inherited? 5 Myths about Autism Genetics

Autism spectrum disorder (ASD) has a strong genetic component, but many misconceptions persist about its inheritance and risk factors. This article debunks five…

Patient Guides · 4 min read

To Spit or Not to Spit? Why to consider providing your saliva with Orchid’s PGT